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Side Effects

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This article neglects to mention possible side effects of Sucralose such as its genotoxicity and diarrhea-inducing effects. Many other sources, such as WebMD confirm and discuss such side effects. 65.183.164.194 (talk) 11:44, 27 June 2023 (UTC)[reply]

Feel free to add information about side effects - if you have some reviews complying with WP:MEDRS and WP:BURDEN. Thanks JimRenge (talk) 12:24, 27 June 2023 (UTC)[reply]
A new study suggests serious side effects [[1]] — Preceding unsigned comment added by 84.202.48.248 (talk) 07:36, 29 June 2023 (UTC)[reply]
And there are people out there like me that have a severe allergic reaction to artificial sweeteners, this one included.....so anaphylactic shock is the at the top of the list for me for side effects, and most food companies do NOT list artificial sweeteners as an allergen. 72.240.196.141 (talk) 23:43, 16 May 2024 (UTC)[reply]
Anaphylaxis with sucralose is unknown in the medical literature. If you had a reaction, it is more likely to have been with some confounding nutrient in what you ate or, least likely, with Splenda which is not the same thing as sucralose, in spite of the confusing wording of this article. Splenda has bulking carbs added, hundreds of times the mass of the sucralose proper.
If you did happen to come across actual pure sucralose, the stuff degrades notoriously after exposure to air and turns bitter. A reaction is distantly possible to a degraded substance in the opened container of sucralose, but you'd know when you tasted it. JohndanR (talk) 20:54, 12 September 2024 (UTC)[reply]

Calorific content

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This article says that sucralose contains 3 calories per gram, which I think is incorrect. The 3 calories comes from reference [3] which is actually for Splenda, not pure sucralose. Other sources e.g. https://www.splenda.com.au/faq/ say that sucralose has "no calories" but given that (according to other sections of this article) some of the sucralose is metalbolised, I'm not sure if it's actually zero calories or just a very small number. Wesli 1 (talk) 22:05, 28 June 2024 (UTC)[reply]

The USDA nutrition data page is entitled "Sweeteners, tabletop, sucralose, SPLENDA packets", i.e., Sucralose is Splenda, which is the brand name. One gram (a tabletop packet) of Splenda supplies 3 calories or essentially no calorie content of significance. Zefr (talk) 22:25, 28 June 2024 (UTC)[reply]
Splenda is not pure sucralose. Splenda is a mix of sucralose and sugars (maltodextrin, dextrose, and/or lactose, depending on the type of Splenda) and the calories come from those sugars, not from the sucralose. Wesli 1 (talk) 04:05, 29 June 2024 (UTC)[reply]
The faq you provided and the article section on calorie content explain adequately that the minimal addition of a bulking agent has a non-significant calorie effect on the sweetener. Otherwise, the definition of sucralose itself is clear in the chemistry section. Zefr (talk) 04:59, 29 June 2024 (UTC)[reply]
You're clearly speaking with no understanding of the actual material you're looking at, dude. The bulking agent makes up ALL of the calories--it has a "non-significant calorie effect" specifically because the total number of calories is still very low. In other words, the FAQ is only worded that way to indicate that you're not suddenly eating something highly caloric just because of the bulking agent. Sucralose is literally not a carbohydrate, yet all of the splenda packet's calories as documented from this exact source come from its carbohydrates. --47.152.51.174 (talk) 19:39, 25 July 2024 (UTC)[reply]
The article, and (irresponsibly) USDA, are conflating Sucralose and Splenda. The opening should be re-written, and the USDA reference should be deleted. The bulking carbs in Splenda are hundreds of times the weight of its Sucralose (trichlorosucrose [for the short name]) ingredient, and even more of the volume.
The USDA may as well consider bread and wheat about the same thing. JohndanR (talk) 20:36, 12 September 2024 (UTC)[reply]
You can dispute the information more credibly if you have a WP:RS source to support it. Otherwise, it's your opinion which is insufficient for a change in the article. Zefr (talk) 20:49, 12 September 2024 (UTC)[reply]

Aggressive archiving of discussions on genotoxicity

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Be advised: It seems as if there are individuals (some utilizing bots) extremely opposed to both the addition of genotoxicity to the article, as well as the discussion of genotoxicity here on the talk page. Any additions to the article discussing genotoxicity are immediately reverted, and discussions on the talk page are quickly archived. 2600:1008:B21C:8E1D:78BD:46FF:FEEA:87D6 (talk) 04:43, 27 September 2024 (UTC)[reply]

Discussions are archived only if they have been inactive for 90 days. Any medical-related statement added to the article absolutely must be cited to a WP:MEDRS compliant source. Otherwise such statements will be reverted. It's that simple. ~Anachronist (talk) 05:20, 27 September 2024 (UTC)[reply]